Boswellic acid acetate induces apoptosis through caspase-mediated pathways in myeloid leukemia cells
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Boswellic acid acetate induces apoptosis through caspase-mediated pathways in myeloid leukemia cells.
The mechanism of the cytotoxic effect of boswellic acid acetate, a 1:1 mixture of alpha-boswellic acid acetate and beta-boswellic acid acetate, isolated from Boswellia carterri Birdw on myeloid leukemia cells was investigated in six human myeloid leukemia cell lines (NB4, SKNO-1, K562, U937, ML-1, and HL-60 cells). Morphologic and DNA fragmentation assays indicated that the cytotoxic effect of ...
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ژورنال
عنوان ژورنال: Molecular Cancer Therapeutics
سال: 2005
ISSN: 1535-7163,1538-8514
DOI: 10.1158/1535-7163.mct-03-0266